Search results for "Interval data"

showing 2 items of 2 documents

Association of derived neutrophil-to-lymphocyte ratio (dNLR) with pathological complete response (pCR) after neoadjuvant chemotherapy (CT)

2019

Abstract Background dNLR is a novel biomarker associated with clinical outcome in solid tumors including early stage breast cancer (BC). Here we report the association of dNLR with pCR in triple-negative (TN) and luminal BC patients (pts) treated with neoadjuvant CT. Methods This was a retrospective analysis of two randomized studies (GEICAM/2006-03 - NCT00432172 and ETNA - NCT01822314) involving 821 pts with early stage (>2cm) or locally advanced TN or luminal BC receiving anthracycline/taxane-based CT +/- carboplatin (GEICAM/2006-03) or nab-paclitaxel/paclitaxel followed by anthracycline regimen (ETNA). dNLR was calculated as the ratio of neutrophils and the difference between total leuko…

Anthracycline Antibioticsmedicine.medical_specialtybusiness.industryLocally advancedHematologyBreast cancer stage iPeripheral bloodInterval dataContinuous variableOncologyFamily medicineRetrospective analysisMedicinebusinesshealth care economics and organizationsComplete responseAnnals of Oncology
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Ramucirumab in patients with advanced hepatocellular carcinoma (HCC) and elevated alpha fetoprotein (AFP): An exposure-response analysis

2019

Sorafenibmedicine.medical_specialtyElevated alpha-fetoproteinbusiness.industryHematologymedicine.diseaseGastroenterologyRamucirumabInterval dataOncologyInternal medicineHepatocellular carcinomaMedicineIn patientProgression-free survivalbusinessExposure responsemedicine.drugAnnals of Oncology
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